Metal-Free Oxidation of Urazole and 1,4-Dihydropyridine Derivatives Under Mild and Heterogeneous Conditions by Nitro Urea, Derived from Urea Nitrate, and Silica Sulfuric Acid

Title: Metal-Free Oxidation of Urazole and 1,4-Dihydropyridine Derivatives Under Mild and Heterogeneous Conditions by Nitro Urea, Derived from Urea Nitrate, and Silica Sulfuric Acid

Volume: 7 Issue: 3

Author(s): Arash Ghorbani-Choghamarani, Mohammad A. Zolfigol, Maryam Hajjami, Shahrbanoo Rastgoo and Shadpour Mallakpour

Affiliation:

Keywords: Urazole, 1,4-dihydropyridine, urea nitrate, nitro urea, silica sulfuric acid

Abstract: Mild combination of nitro urea, derived from urea nitrate, and silica sulfuric acid (SiO2OSO3H) might act as an efficient oxidizing media, which could be able to oxidize different types of heterocyclic compounds including urazoles and 1,4-dihydropyridines. The process presented here is operationally simple, environmentally benign, and reactions have been mildly carried out in dichloromethane at room temperature.

Cite this article as:

Ghorbani-Choghamarani Arash, A. Zolfigol Mohammad, Hajjami Maryam, Rastgoo Shahrbanoo and Mallakpour Shadpour, Metal-Free Oxidation of Urazole and 1,4-Dihydropyridine Derivatives Under Mild and Heterogeneous Conditions by Nitro Urea, Derived from Urea Nitrate, and Silica Sulfuric Acid, Letters in Organic Chemistry 2010; 7 (3) . https://dx.doi.org/10.2174/157017810791112450