An Environment-Friendly and Efficient Method for Aldol Condensation Catalyzed by L-Lysine in Pure Water

Yan      Zhang; Man   Gang   Wang; Jun      Liang; Zhi   Cai   Shang

doi:10.2174/157017810790533995

Abstract

This is a new example of a nonmetallic small-molecule catalyst for direct intermolecular aldol reactions. We found L-lysine is an effective catalyst for this condensation between unmodified acetone and a variety of aldehydes in the presence of pure water. This green catalyst system could be reused.

Keywords: L-lysine, organo-catalysis, aldol reaction, green chemistry

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Letters in Organic Chemistry

Title: An Environment-Friendly and Efficient Method for Aldol Condensation Catalyzed by L-Lysine in Pure Water

Volume: 7 Issue: 1

Author(s): Yan Zhang, Man Gang Wang, Jun Liang and Zhi Cai Shang

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Keywords: L-lysine, organo-catalysis, aldol reaction, green chemistry

Abstract: This is a new example of a nonmetallic small-molecule catalyst for direct intermolecular aldol reactions. We found L-lysine is an effective catalyst for this condensation between unmodified acetone and a variety of aldehydes in the presence of pure water. This green catalyst system could be reused.

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Zhang Yan, Wang Gang Man, Liang Jun and Shang Cai Zhi, An Environment-Friendly and Efficient Method for Aldol Condensation Catalyzed by L-Lysine in Pure Water, Letters in Organic Chemistry 2010; 7 (1) . https://dx.doi.org/10.2174/157017810790533995