Synthesis and Evaluation of C-28 Oleanolic Acid Derivatives as Inhibitors of Glycogen Phosphorylase

Title: Synthesis and Evaluation of C-28 Oleanolic Acid Derivatives as Inhibitors of Glycogen Phosphorylase

Volume: 7 Issue: 2

Author(s): Keguang Cheng, Chao Wang, Jun Liu, Juan Xie and Hongbin Sun

Affiliation:

Keywords: Glycogen phosphorylase, Oleanolic acid, C-28 derivatives, Synthesis, Inhibition

Abstract: Synthesis and evaluation of C-28 oleanolic acid derivatives as novel inhibitors of glycogen phosphorylase have been described. The results of glycogen phosphorylase inhibition assay and structure-activity relationship (SAR) analysis are also discussed.

Cite this article as:

Cheng Keguang, Wang Chao, Liu Jun, Xie Juan and Sun Hongbin, Synthesis and Evaluation of C-28 Oleanolic Acid Derivatives as Inhibitors of Glycogen Phosphorylase, Letters in Drug Design & Discovery 2010; 7 (2) . https://dx.doi.org/10.2174/157018010790225921

DOI https://dx.doi.org/10.2174/157018010790225921	Print ISSN 1570-1808
Publisher Name Bentham Science Publisher	Online ISSN 1875-628X