The Antisense Oligonucleotides Decrease Expression of the Cellular Prion

Title: The Antisense Oligonucleotides Decrease Expression of the Cellular Prion

Volume: 7 Issue: 1

Author(s): Vitalii V. Stadnyk, Lyudmyla A. Izyumova, Yuriy A. Rzhepetskiy, Chrystyna Ya Mayor and Vasyl V. Vlizlo

Affiliation:

Keywords: Cellular prion, Antisense oligodesoxyribonucleotides, Immunoliposomes

Abstract: The subject of this work was an inhibition of cellular prion expression in vitro and in vivo by antisense oligodeoxyribonucleotides, incorporated into cationic immunoliposomes. It was shown that asODNs are able to reduce the level of PrPc expression in vitro and in vivo.

Cite this article as:

Stadnyk V. Vitalii, Izyumova A. Lyudmyla, Rzhepetskiy A. Yuriy, Mayor Ya Chrystyna and Vlizlo V. Vasyl, The Antisense Oligonucleotides Decrease Expression of the Cellular Prion, Letters in Drug Design & Discovery 2010; 7 (1) . https://dx.doi.org/10.2174/157018010789869299