The In Situ Structural Characterization of the Influenza A Virus Matrix M1 Protein within a Virion

Title: The In Situ Structural Characterization of the Influenza A Virus Matrix M1 Protein within a Virion

Volume: 16 Issue: 11

Author(s): Alexander V. Shishkov, Elena N. Bogacheva, Alexey A. Dolgov, Alexey L. Chulichkov, Denis G. Knyazev, Natalia V. Fedorova, Alexander L. Ksenofontov, Larisa V. Kordyukova, Elena V. Lukashina, Vladimir M. Mirsky and Lyudmila A. Baratova

Affiliation:

Keywords: Influenza A virus, matrix M1 protein, secondary structure prediction, tritium planigraphy, surface plasmon resonance spectroscopy, three-dimensional modeling

Abstract: The first attempt has been made to suggest a model of influenza A virus matrix M1 protein spatial structure and molecule orientation within a virion on the basis of tritium planigraphy data and theoretical prediction results. Limited in situ proteolysis of the intact virions with bromelain and surface plasmon resonance spectroscopy study of the M1 protein interaction with lipid coated surfaces were used for independent confirmation of the proposed model.

Cite this article as:

Shishkov V. Alexander, Bogacheva N. Elena, Dolgov A. Alexey, Chulichkov L. Alexey, Knyazev G. Denis, Fedorova V. Natalia, Ksenofontov L. Alexander, Kordyukova V. Larisa, Lukashina V. Elena, Mirsky M. Vladimir and Baratova A. Lyudmila, The In Situ Structural Characterization of the Influenza A Virus Matrix M1 Protein within a Virion, Protein & Peptide Letters 2009; 16 (11) . https://dx.doi.org/10.2174/092986609789353682

DOI https://dx.doi.org/10.2174/092986609789353682	Print ISSN 0929-8665
Publisher Name Bentham Science Publisher	Online ISSN 1875-5305