Regio- and Stereoselective Ring Opening of Allylic Epoxides

Title: Regio- and Stereoselective Ring Opening of Allylic Epoxides

Volume: 6 Issue: 3

Author(s): Mauro Pineschi, Ferruccio Bertolini, Valeria Di Bussolo and Paolo Crotti

Affiliation:

Keywords: Allylic epoxides, nucleophilic ring opening, heteronucleophiles, carbon nucleophiles, regioselectivity, stereoselectivity, enantioselectivity

Abstract: Three-membered heterocyclic rings offer a powerful combination of reactivity, stability, availability, and atom economy. In fact, the asymmetric ring opening of allylic epoxides with nucleophiles of different kinds, as will be discussed in this Review, offers the possibility of generating valuable chiral non-racemic building blocks in a very simple manner and in a stereodefined fashion.

Cite this article as:

Pineschi Mauro, Bertolini Ferruccio, Di Bussolo Valeria and Crotti Paolo, Regio- and Stereoselective Ring Opening of Allylic Epoxides, Current Organic Synthesis 2009; 6 (3) . https://dx.doi.org/10.2174/157017909788921862