Prion Protein Peptides as Vaccines

M.      Ghielmetti; T.      Vranac; V.   Curin   Serbec

doi:10.2174/138955709787847903

Abstract

Investigations into the immunogenicity of the prion protein are ongoing. To combat its pathological isoform without affecting the cellular protein is a challenge in prion research. We here summarize the studies in which prion protein peptides have been used for immunization, to thus determine the most immunogenic parts of the prion protein.

Keywords: Prion protein, peptides, epitope prediction, immune response, vaccine

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