Screening of Dipeptides Having Central Functions for Excitation and Sedation

H.      Yamane; D.   M.   Denbow; M.      Furuse

doi:10.2174/1389557510909030300

Abstract

The naturally-occurring dipeptide carnosine (β-alanyl-L-histidine) and the tripeptide glutathione (L-γglutamyl- L-cysteinylglycine) are found extensively in animal tissues such as brain and skeletal muscle. Central functions for excitation and sedation of them and their derivatives were screened.

Keywords: Dipeptides, carnosine, glutathione, excitation, sedation

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Mini-Reviews in Medicinal Chemistry

Title: Screening of Dipeptides Having Central Functions for Excitation and Sedation

Volume: 9 Issue: 3

Author(s): H. Yamane, D. M. Denbow and M. Furuse

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Keywords: Dipeptides, carnosine, glutathione, excitation, sedation

Abstract: The naturally-occurring dipeptide carnosine (β-alanyl-L-histidine) and the tripeptide glutathione (L-γglutamyl- L-cysteinylglycine) are found extensively in animal tissues such as brain and skeletal muscle. Central functions for excitation and sedation of them and their derivatives were screened.

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Yamane H., Denbow M. D. and Furuse M., Screening of Dipeptides Having Central Functions for Excitation and Sedation, Mini-Reviews in Medicinal Chemistry 2009; 9 (3) . https://dx.doi.org/10.2174/1389557510909030300