Abstract
In recent years, furan-2(5H)-ones have attracted considerable attention as synthetic target. This subunit is present in a large number of natural products, which display a wide range of biological activities, and is present in a number of drugs with diverse biological activities, such as antifungal, antibacterial and anti-inflammatory. It can also be used as synthetic intermediate. This review describes recent synthetic methodologies for preparation of furan-2(5H)-ones, as well as their application in the total synthesis of natural products with this subunit.
Keywords: furan-2(5h)-ones, biologic activity, natural products, synthetic methodologies
Mini-Reviews in Organic Chemistry
Title: The Furan-2(5H)-ones: Recent Synthetic Methodologies and its Application in Total Synthesis of Natural Products
Volume: 2 Issue: 2
Author(s): Marcus Vinicius Nora De Souza
Affiliation:
Keywords: furan-2(5h)-ones, biologic activity, natural products, synthetic methodologies
Abstract: In recent years, furan-2(5H)-ones have attracted considerable attention as synthetic target. This subunit is present in a large number of natural products, which display a wide range of biological activities, and is present in a number of drugs with diverse biological activities, such as antifungal, antibacterial and anti-inflammatory. It can also be used as synthetic intermediate. This review describes recent synthetic methodologies for preparation of furan-2(5H)-ones, as well as their application in the total synthesis of natural products with this subunit.
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Cite this article as:
De Souza Nora Marcus Vinicius, The Furan-2(5H)-ones: Recent Synthetic Methodologies and its Application in Total Synthesis of Natural Products, Mini-Reviews in Organic Chemistry 2005; 2 (2) . https://dx.doi.org/10.2174/1570193053544427
DOI https://dx.doi.org/10.2174/1570193053544427 |
Print ISSN 1570-193X |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6298 |
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