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Letters in Organic Chemistry

Editor-in-Chief

ISSN (Print): 1570-1786
ISSN (Online): 1875-6255

Efficient Microwave Solvent-Free Synthesis of Flavones, Chromones, Coumarins and Dihydrocoumarins

Author(s): Daniel O. Bennardi, Diego M. Ruiz, Gustavo P. Romanelli, Graciela T. Baronetti, Horacio J. Thomas and Juan C. Autino

Volume 5, Issue 8, 2008

Page: [607 - 615] Pages: 9

DOI: 10.2174/157017808786857570

Price: $65

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Abstract

Simple, clean, environmentally friendly procedures for the solvent-free preparation of coumarins, dihydrocoumarins, flavones and chromones under microwave heating are described. Silica-supported Wells-Dawson heteropolyacid (H6P2W18O62·24 H2O) was employed as catalyst. High selectivity, very good yields and short reaction times were obtained. The results are compared with those of the reactions performed under conventional heating.

Keywords: Acid catalysis, chromones, coumarins, dihydrocoumarins, flavones, microwave, solvent-free, Wells-Dawson heteropolyacid


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