Aptabodies – New Type of Artificial Receptors for Detection Proteins

Title: Aptabodies – New Type of Artificial Receptors for Detection Proteins

Volume: 15 Issue: 8

Author(s): T. Hianik, A. Porfireva, I. Grman and G. Evtugyn

Affiliation:

Keywords: DNA aptamers, Hybridization, Human thrombin, Multiwalled carbon nanotubes, Biosensor, Electrochemical quartz crystal microbalance

Abstract: We report on a new type of artificial receptor formed by hybridization of two DNA aptamers for human thrombin (aptabody). This aptasensor based on multiwalled carbon nanotubes allowed us to detect thrombin with detection limit of 0.3 nM, which was 3 times better in comparison with conventional aptamer.

Cite this article as:

Hianik T., Porfireva A., Grman I. and Evtugyn G., Aptabodies – New Type of Artificial Receptors for Detection Proteins, Protein & Peptide Letters 2008; 15 (8) . https://dx.doi.org/10.2174/092986608785203656

DOI https://dx.doi.org/10.2174/092986608785203656	Print ISSN 0929-8665
Publisher Name Bentham Science Publisher	Online ISSN 1875-5305