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Letters in Drug Design & Discovery

Editor-in-Chief

ISSN (Print): 1570-1808
ISSN (Online): 1875-628X

Antibacterial Pleuromutilin Derivatives based on Alternate Core Structures:Arigoni and Birch Chemistry Revisited

Author(s): Dane M. Springer, Jason T. Goodrich, Bing-Yu Luh, Joanne J. Bronson, Qi Gao, Stella Huang, Kenneth DenBleyker, Thomas J. Dougherty and Joan Fung-Tomc

Volume 5, Issue 5, 2008

Page: [327 - 331] Pages: 5

DOI: 10.2174/157018008784912063

Price: $65

Abstract

Pleuromutilin derivatives comprised of varied core structures have been synthesized. Many of the compounds described were found to have surprisingly good antibacterial activity in vitro.


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