Effect of Cosolvents on the Stabilization of Bioactive Peptides from Bovine Milk α-Casein

Title: Effect of Cosolvents on the Stabilization of Bioactive Peptides from Bovine Milk α-Casein

Volume: 15 Issue: 4

Author(s): Sistla Srinivas and Vishweshwaraiah Prakash

Affiliation:

Keywords: α-casein, cosolvents, polyols, peptides, stabilization, ACE activity, antioxidant activity

Abstract: Peptides with more than one biological activity are many a times multifunctional peptides. Two peptides with multifunctional properties from αS2-casein were stabilized in presence of cosolvents for their biological activities like ACE inhibition activity and antioxidant activity. These bioactive peptides in cosolvents were also thermostable. Infra red spectra of peptides in cosolvents reveal no change in the secondary structure in presence of cosolvents. Correlation between sequence, structure and composition of peptides on biological activities were studied.

Cite this article as:

Srinivas Sistla and Prakash Vishweshwaraiah, Effect of Cosolvents on the Stabilization of Bioactive Peptides from Bovine Milk α-Casein, Protein & Peptide Letters 2008; 15 (4) . https://dx.doi.org/10.2174/092986608784246416

DOI https://dx.doi.org/10.2174/092986608784246416	Print ISSN 0929-8665
Publisher Name Bentham Science Publisher	Online ISSN 1875-5305