Chemistry of Norbornane/ene and Heteronorbornane/ene β-Amino Acids

Ferenc      Csende; Ferenc      Fulop; Geza      Stajer

doi:10.2174/157017908784221576

Abstract

The structures, biological properties, preparations and synthetic applications of norbornane/ene bicyclic and heteroatombridged β-amino acids are discussed. These compounds are rare and unique β-alanine derivatives which can be used as bifunctional synthons for the preparation of heterocycles. Through peptidation, they form oligopeptide-like molecules with special helical structures.

Keywords: (Hetero)bicyclic β-amino acids, biological activity, heterocycles, retro diels-alder reactions, ugi reactions, peptide syntheses

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Current Organic Synthesis

Title: Chemistry of Norbornane/ene and Heteronorbornane/ene β-Amino Acids

Volume: 5 Issue: 2

Author(s): Ferenc Csende, Ferenc Fulop and Geza Stajer

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Keywords: (Hetero)bicyclic β-amino acids, biological activity, heterocycles, retro diels-alder reactions, ugi reactions, peptide syntheses

Abstract: The structures, biological properties, preparations and synthetic applications of norbornane/ene bicyclic and heteroatombridged β-amino acids are discussed. These compounds are rare and unique β-alanine derivatives which can be used as bifunctional synthons for the preparation of heterocycles. Through peptidation, they form oligopeptide-like molecules with special helical structures.

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Csende Ferenc, Fulop Ferenc and Stajer Geza, Chemistry of Norbornane/ene and Heteronorbornane/ene β-Amino Acids, Current Organic Synthesis 2008; 5 (2) . https://dx.doi.org/10.2174/157017908784221576