Ring Closing Metathesis as an Efficient Protocol for the Stereoselective Synthesis of Spiro C-Linked 4-Deoxy Disaccharides

Title: Ring Closing Metathesis as an Efficient Protocol for the Stereoselective Synthesis of Spiro C-Linked 4-Deoxy Disaccharides

Volume: 5 Issue: 2

Author(s): Jakkidi J. Reddy, Asra Begum, Pagadala Jayaprakash, Gangavaram V.M. Sharma and Ajit C. Kunwar

Affiliation:

Keywords: Grubbs catalyst, ring closing metathesis, stereoselective synthesis, spiro C-linked 4-deoxy disaccharides, bisallylic chirons

Abstract: Ring closing metathesis protocol on bis-allylic chirons derived from sugars was utilized for the stereoselective synthesis of spiro C-linked deoxy disaccharides. Uloses derived from D-xylose and L-sorbose were converted into bisallylic derivatives, which on RCM gave the spiro-pyrane rings. The xylose-derived spiro-pyrane on sequential oxidations was converted into new deoxy spiro C-disaccharides.

Cite this article as:

Reddy J. Jakkidi, Begum Asra, Jayaprakash Pagadala, Sharma V.M. Gangavaram and Kunwar C. Ajit, Ring Closing Metathesis as an Efficient Protocol for the Stereoselective Synthesis of Spiro C-Linked 4-Deoxy Disaccharides, Letters in Organic Chemistry 2008; 5 (2) . https://dx.doi.org/10.2174/157017808783743939