Pyranose N-Glycosyl Amines: Emerging Targets With Diverse Biological Potential

Title: Pyranose N-Glycosyl Amines: Emerging Targets With Diverse Biological Potential

Volume: 8 Issue: 2

Author(s): Peter Norris

Affiliation:

Keywords: N-Glycosyl amine, N-glycosyl amide, N-glycosylated heterocycles

Abstract: Interest in the chemistry and biological properties of non-nucleoside N-glycosidic compounds has gathered pace over the past several years; the occurrence of the N-glycoside moiety in glycoproteins and a range of active natural products has prompted the synthesis of a diverse spectrum of related materials with promising potential in medicinal chemistry. Particularly prominent has been the synthesis of novel N-glycosyl amides, 1,2,3-triazoles, and progress in the construction and diversification of natural products such as the mannopeptimycins and indolocarbazoles, each of which are discussed in this article.

Cite this article as:

Norris Peter, Pyranose N-Glycosyl Amines: Emerging Targets With Diverse Biological Potential, Current Topics in Medicinal Chemistry 2008; 8 (2) . https://dx.doi.org/10.2174/156802608783378837