A Facile Synthesis of Lipo-Chitopentaose Nodulation Factor

Title: A Facile Synthesis of Lipo-Chitopentaose Nodulation Factor

Volume: 4 Issue: 8

Author(s): G.-L. Huang and Kongliang Wong

Affiliation:

Keywords: Lipo-chitopentaose nodulation factor, chemo-enzymatic synthesis, degradation velocity, chitinase

Abstract: We prepared the penta-N-acetyl-chitopentaose 2 by using recombinant Escherichia coli (E. coli) strains harboring the nodC gene (encoding chitooligosaccharide synthase) from Azorhizobium caulinodans. The deacetylase NodB removed the N-acetyl moiety from the nonreducing terminus of 2 to give tetra-N-acetyl-chitopentaose 3. N-Acylation of 3 with stearyl chloride was performed in DMF containing water and provided the corresponding lipo-chitopentaose nodulation factor 4.

Cite this article as:

Huang G.-L. and Wong Kongliang, A Facile Synthesis of Lipo-Chitopentaose Nodulation Factor, Letters in Organic Chemistry 2007; 4 (8) . https://dx.doi.org/10.2174/157017807782795475