Ceruloplasmin, the Unique Multi-Copper Oxidase of Vertebrates

Title: Ceruloplasmin, the Unique Multi-Copper Oxidase of Vertebrates

Volume: 8 Issue: 3

Author(s): Giovanni Musci

Affiliation:

Keywords: CERULOPLASMIN, MULTI-COPPER OXIDASE, ascorbate oxidase (C), Coprinus cinereus laccase, ascorbate oxidase, aceruloplasminemia, Copper transport, ferroxidase, multi-copper ferroxidase

Abstract: This review shortly summarizes the structural and functional properties of ceruloplasmin, the blue copper oxidase of vertebrates. Particular emphasis will be put on the unique copper stoichiometry of ceruloplasmin in comparison to all other multi-copper oxidases, and different hypotheses will be discussed to explain the apparently useless redundancy of type 1 copper ions in the vertebrate oxidase.

Cite this article as:

Musci Giovanni, Ceruloplasmin, the Unique Multi-Copper Oxidase of Vertebrates, Protein & Peptide Letters 2001; 8 (3) . https://dx.doi.org/10.2174/0929866013409517