EPITOPE-PARATOPE RECOGNITION BY KNOWLEDGE BASED CORRELATION MAPPING USING HOPFIELD NETWORK

Title: EPITOPE-PARATOPE RECOGNITION BY KNOWLEDGE BASED CORRELATION MAPPING USING HOPFIELD NETWORK

Volume: 8 Issue: 4

Author(s): Rajani R. Joshi

Affiliation:

Keywords: EPITOPE-PARATOPE, knowledge based correlation mapping (KBCM), Epitope, Paratope, immunoglobulins

Abstract: The knowledge based correlation mapping (KBCM) is devised here as a unified measure of the information on antigen-antibody complexes available in the Protein Data Banks. This mapping is estimated from a random training sample using a Hopfield Network while representing the epitope and paratope in a complex as 3-dimensional attributed graphs. Identification of paratopes on immunoglobulins against given epitopes is carried out using pattern matching on Hopfield Network with the help of the KBCM.

Cite this article as:

Joshi R. Rajani, EPITOPE-PARATOPE RECOGNITION BY KNOWLEDGE BASED CORRELATION MAPPING USING HOPFIELD NETWORK, Protein & Peptide Letters 2001; 8 (4) . https://dx.doi.org/10.2174/0929866013409418

DOI https://dx.doi.org/10.2174/0929866013409418	Print ISSN 0929-8665
Publisher Name Bentham Science Publisher	Online ISSN 1875-5305