Quantitative Structure-Activity Relationship (QSAR) Paradigm - Hansch Era to New Millennium

Title: Quantitative Structure-Activity Relationship (QSAR) Paradigm - Hansch Era to New Millennium

Volume: 1 Issue: 2

Author(s): Asim Kumar Debnath

Affiliation:

Keywords: quantitative structure-activity relationship (QSAR), Hologram QSAR, Inverse QSAR, Binary QSAR, QSAR METHODS

Abstract: The analysis of structure-activity relationships started probably more than hundred years ago but the concept of quantitatively correlating physicochemical properties of molecules with their biological activities, termed as quantitative structure-activity relationship (QSAR), was initiated by Corwin Hansch and his groups in early 1960. Many new methods have emerged since then. The concept evolved from 2D QSAR to 3D QSAR and lately another dimension (4D QSAR) has been added. This evolution is briefly reviewed here.

Cite this article as:

Debnath Kumar Asim, Quantitative Structure-Activity Relationship (QSAR) Paradigm - Hansch Era to New Millennium, Mini-Reviews in Medicinal Chemistry 2001; 1 (2) . https://dx.doi.org/10.2174/1389557013407061