Nucleolin Binds to a cis-Active Region in the Human Desmocollin 2 Promoter

Title: Nucleolin Binds to a cis-Active Region in the Human Desmocollin 2 Promoter

Volume: 8 Issue: 5

Author(s): Paresh L. Gadhavi, Steven Howell, Anthony I. Magee and Roger S. Buxton

Affiliation:

Keywords: NUCLEOLIN, DESMOCOLLIN 2 PROMOTER, Glycoproteins, desmosomal cadherins desmocollins (DSC), desmogleins (DSG), plakoglobin (PG), plakophilin (PKP), desmoplakin (DP)

Abstract: Affinity chromatography using oligo DNA from a cis-active region (-453 / -389) of the human DSC2 promoter was used to isolate a protein from human CaCo-2 epithelial cells expressing DSC2. The protein was SDS-PAGE purified, trypsinized and analyzed by MALDI-TOF mass spectrometry. Peptide mass fingerprinting identified the protein as nucleolin, a ubiquitously expressed protein involved in gene regulation

Cite this article as:

Gadhavi L. Paresh, Howell Steven, Magee I. Anthony and Buxton S. Roger, Nucleolin Binds to a cis-Active Region in the Human Desmocollin 2 Promoter, Protein & Peptide Letters 2001; 8 (5) . https://dx.doi.org/10.2174/0929866013409247