Abstract
Multiple sclerosis is a chronic inflammatory disease of the central nervous system. While the molecular basis of the disease is still unknown, research effort is currently under progress to prevent or ameliorate its effects. There are two major approaches currently in the pursuing of improved therapeutics for the treatment of multiple sclerosis. The first approach focuses on peptide or mimetic therapy and the second on immunotherapy by preventing or controlling disease through the release of appropriate cytokines.
Keywords: Multiple Sclerosis, Autoimmunity, Corticosteroids, Cytokines, Cytotoxic immunosuppressants, Antidepressants (SSRIs), Mannan Conjugates
Mini-Reviews in Medicinal Chemistry
Title: Designing Peptide Mimetics for the Treatment of Multiple Sclerosis
Volume: 1 Issue: 3
Author(s): J. Matsoukas, V. Apostolopoulos and T. Mavromoustakos
Affiliation:
Keywords: Multiple Sclerosis, Autoimmunity, Corticosteroids, Cytokines, Cytotoxic immunosuppressants, Antidepressants (SSRIs), Mannan Conjugates
Abstract: Multiple sclerosis is a chronic inflammatory disease of the central nervous system. While the molecular basis of the disease is still unknown, research effort is currently under progress to prevent or ameliorate its effects. There are two major approaches currently in the pursuing of improved therapeutics for the treatment of multiple sclerosis. The first approach focuses on peptide or mimetic therapy and the second on immunotherapy by preventing or controlling disease through the release of appropriate cytokines.
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Cite this article as:
Matsoukas J., Apostolopoulos V. and Mavromoustakos T., Designing Peptide Mimetics for the Treatment of Multiple Sclerosis, Mini-Reviews in Medicinal Chemistry 2001; 1 (3) . https://dx.doi.org/10.2174/1389557013406873
DOI https://dx.doi.org/10.2174/1389557013406873 |
Print ISSN 1389-5575 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5607 |
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