Structural Insight Into Oxybenzotriazole Based Coupling Reagents

Title: Structural Insight Into Oxybenzotriazole Based Coupling Reagents

Volume: 8 Issue: 1

Author(s): T. K. Srivastava, W. Haq, S. Bhanumati, D. Velmurugan, U. Sharma, N. R. Jagannathan and S. B. Katti

Affiliation:

Keywords: Oxybenzotriazole Based Coupling Reagents

Abstract: Present work encompasses a detailed solution and solid phase NMR spectroscopic studies on oxybenzotriazole based coupling reagents namely HBTU (1), NBTU (2) and BOP (3). The present finding unequivocally establish that the correct structure of oxybenzotriazole based coupling reagents both in the solution and solid states are benzotriazolyl N-oxides as shown in 1a, 2a and 3a and not the uronium form as represented in the current literature.

Cite this article as:

Srivastava K. T., Haq W., Bhanumati S., Velmurugan D., Sharma U., Jagannathan R. N. and Katti B. S., Structural Insight Into Oxybenzotriazole Based Coupling Reagents, Protein & Peptide Letters 2001; 8 (1) . https://dx.doi.org/10.2174/0929866013409661

DOI https://dx.doi.org/10.2174/0929866013409661	Print ISSN 0929-8665
Publisher Name Bentham Science Publisher	Online ISSN 1875-5305