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Protein & Peptide Letters

Editor-in-Chief

ISSN (Print): 0929-8665
ISSN (Online): 1875-5305

Study on interaction between Duodenase - Protease with Dual Specificity and Inhibitors of Bowman-Birk Family

Author(s): Inna P. Gladysheva, Natalia A. Popykina, Tatyana S. Zamolodchikova and Natalia I. Larionova

Volume 9, Issue 2, 2002

Page: [139 - 144] Pages: 6

DOI: 10.2174/0929866023408878

Price: $65

Abstract

The interaction between duodenase and inhibitors of Bowman-Birk type from soybeans (BBI) and lima beans (LBI) was investigated. Duodenase was shown to interact only with antichymotrypsin site of these inhibitors. The inhibition constants of duodenase by BBI, LBI, BBI-trypsin and LBI trypsin complexes were 4, 23, 400, 600 nM respectively.

Keywords: bowman, birk family, soybeams, antichymotrypsin site, bbi, lbi trypsin complexes


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