Abstract
Steroid hormones may possess two distinct actions, a delayed genomic influence and the rapid nongenomic effects, which may act in concert. Nongenomic effect may be mediated by putative membrane receptors or due to allosteric interactions of steroids with membrane proteins (e.g. ionic channels), inducing rapid changes in protein / receptor / channel activation or inhibition.
Keywords: steroid hormone, membrane channel, membrane protein
Mini-Reviews in Medicinal Chemistry
Title: Non-genomic Effects of Steroid Hormones on Membrane Channels
Volume: 2 Issue: 4
Author(s): J. C. Herve
Affiliation:
Keywords: steroid hormone, membrane channel, membrane protein
Abstract: Steroid hormones may possess two distinct actions, a delayed genomic influence and the rapid nongenomic effects, which may act in concert. Nongenomic effect may be mediated by putative membrane receptors or due to allosteric interactions of steroids with membrane proteins (e.g. ionic channels), inducing rapid changes in protein / receptor / channel activation or inhibition.
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Cite this article as:
Herve C. J., Non-genomic Effects of Steroid Hormones on Membrane Channels, Mini-Reviews in Medicinal Chemistry 2002; 2 (4) . https://dx.doi.org/10.2174/1389557023405981
DOI https://dx.doi.org/10.2174/1389557023405981 |
Print ISSN 1389-5575 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5607 |
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