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Protein & Peptide Letters

Editor-in-Chief

ISSN (Print): 0929-8665
ISSN (Online): 1875-5305

Correlation Between Hydrophobicity Sequence and Accessibility Sequence of Membrane Proteins

Author(s): Qiang Xu

Volume 11, Issue 6, 2004

Page: [533 - 537] Pages: 5

DOI: 10.2174/0929866043406427

Price: $65

Abstract

In this paper, we used correlation analysis to quantify the correlations between the hydrophobicity sequence and accessibility sequence of 26 α-helix bundle membrane proteins and 119 transmembrane helices. Statistical significances of these correlations were also assessed. A slightly positive correlation was found in the α-helix bundle membrane proteins due to the contribution of extramembranous domains. No correlation was found in the transmembrane domains.

Keywords: hydrophobicity, accessibility, membrane protein, correlation analysis.


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