Correlation Between Hydrophobicity Sequence and Accessibility Sequence of Membrane Proteins

Qiang      Xu

doi:10.2174/0929866043406427

Abstract

In this paper, we used correlation analysis to quantify the correlations between the hydrophobicity sequence and accessibility sequence of 26 α-helix bundle membrane proteins and 119 transmembrane helices. Statistical significances of these correlations were also assessed. A slightly positive correlation was found in the α-helix bundle membrane proteins due to the contribution of extramembranous domains. No correlation was found in the transmembrane domains.

Keywords: hydrophobicity, accessibility, membrane protein, correlation analysis.

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Protein & Peptide Letters

Title: Correlation Between Hydrophobicity Sequence and Accessibility Sequence of Membrane Proteins

Volume: 11 Issue: 6

Author(s): Qiang Xu

Affiliation:

Keywords: hydrophobicity, accessibility, membrane protein, correlation analysis.

Abstract: In this paper, we used correlation analysis to quantify the correlations between the hydrophobicity sequence and accessibility sequence of 26 α-helix bundle membrane proteins and 119 transmembrane helices. Statistical significances of these correlations were also assessed. A slightly positive correlation was found in the α-helix bundle membrane proteins due to the contribution of extramembranous domains. No correlation was found in the transmembrane domains.

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Xu Qiang, Correlation Between Hydrophobicity Sequence and Accessibility Sequence of Membrane Proteins, Protein & Peptide Letters 2004; 11 (6) . https://dx.doi.org/10.2174/0929866043406427