New Developments on Thromboxane Modulators

Title: New Developments on Thromboxane Modulators

Volume: 4 Issue: 6

Author(s): Jean-Michel Dogne, Julien Hanson, Xavier de Leval, Bernard Masereel, Philippe Kolh and Bernard Pirotte

Affiliation:

Keywords: thromboxane a2, arachidonic acid, thromboxane synthase, prostanoids

Abstract: Thromboxane A2 (TXA2) is a labile product formed from arachidonic acid by cyclooxygenase. The pathogenesis of numerous cardiovascular, pulmonary, and thromboembolic diseases can be related to this metabolite. Therefore, TXA2 modulators have been developed for 20 years. This review will highlight the evolution in the field of TXA2 modulators.

Cite this article as:

Dogne Jean-Michel, Hanson Julien, Leval de Xavier, Masereel Bernard, Kolh Philippe and Pirotte Bernard, New Developments on Thromboxane Modulators, Mini-Reviews in Medicinal Chemistry 2004; 4 (6) . https://dx.doi.org/10.2174/1389557043403684