Abstract
The NK2 receptor (member of the tachykinin receptor family) is mainly located in the smooth muscle of the urinary, respiratory and gastrointestinal tracts, with limited presence in the CNS. This has raised interest in tachykinin NK2 receptor antagonists for the treatment of urological disorders, asthma. This review outlines progress done after 1998 in the field of NK2 small molecule antagonists, both acting on the NK1 / NK2, NK2 / NK3, NK1 / NK2 / NK3 receptors and selective for the NK2 one.
Keywords: nk2 receptor antagonists
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