Selected Recent Advances in the Stereoselective Synthesis of Isoquinoline and β-Carboline Derivatives with the Use of Chiral Auxiliaries of Natural Origin

Title: Selected Recent Advances in the Stereoselective Synthesis of Isoquinoline and β-Carboline Derivatives with the Use of Chiral Auxiliaries of Natural Origin

Volume: 2 Issue: 3

Author(s): Zbigniew Czarnocki, Aleksandra Siwicka and Joanna Szawkalo

Affiliation:

Keywords: stereochemistry, alkaloids, pictet-spengler, bischler-napieralski, enantiomers, diastereomers

Abstract: Various aspects of stereoselective synthesis of tetrahydroisoquinolines and tetrahydro-β-carbolines with the use of natural compounds as chirality sources are reviewed. The following low molecular weight substrates are considered: carbohydrates, isoprenoids, hydroxyacids, alkaloids and amino acids. Examples of various synthetic methodologies that employ the above derivatives as chiral building blocks, chiral auxiliaries or chiral ligands are presented.

Cite this article as:

Czarnocki Zbigniew, Siwicka Aleksandra and Szawkalo Joanna, Selected Recent Advances in the Stereoselective Synthesis of Isoquinoline and β-Carboline Derivatives with the Use of Chiral Auxiliaries of Natural Origin, Current Organic Synthesis 2005; 2 (3) . https://dx.doi.org/10.2174/1570179054368527