Abstract
A gold-catalyzed direct addition of alkynes to active acyl iminium ion, which was generated in situ with an acid chloride, to afford a propargylamides in excellent yields.
Keywords: propargyl amines, enantioselective synthesis, copper-catalyzed addition, solid-phase mannich condensation, copper-mediated coupling, diisopropylethylamine
Letters in Organic Chemistry
Title: Gold-Catalyzed Coupling of Alkynes and Acyl Iminiums
Volume: 2 Issue: 5
Author(s): Chunmei Wei and Chao-Jun Li
Affiliation:
Keywords: propargyl amines, enantioselective synthesis, copper-catalyzed addition, solid-phase mannich condensation, copper-mediated coupling, diisopropylethylamine
Abstract: A gold-catalyzed direct addition of alkynes to active acyl iminium ion, which was generated in situ with an acid chloride, to afford a propargylamides in excellent yields.
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Cite this article as:
Wei Chunmei and Li Chao-Jun, Gold-Catalyzed Coupling of Alkynes and Acyl Iminiums, Letters in Organic Chemistry 2005; 2 (5) . https://dx.doi.org/10.2174/1570178054405959
DOI https://dx.doi.org/10.2174/1570178054405959 |
Print ISSN 1570-1786 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6255 |
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