Cell-Based Biosensors in Clinical Chemistry

Spiridon   E.   Kintzios

doi:10.2174/138955707782110141

Abstract

Cell-based biosensors represent the next revolution in medical diagnostics, offering a number of significant advantages, such as high speed, portability and low cost. The present review focuses on the most successful technologies used for the detection of ultra-low concentrations of bioactive analytes (such as metabolic markers and pathogens) in clinical samples.

Keywords: Bioelectric recognition, cell-based sensors, cell transfection, hepatitis virus B (HBV), hepatitis virus C (HCV), high-throughput screening systems (HSTSS), membrane-engineering, superoxide anion