An Efficient Novel Ligand for Copper-Catalyzed Formation of Diaryl Ethers

Title: An Efficient Novel Ligand for Copper-Catalyzed Formation of Diaryl Ethers

Volume: 4 Issue: 7

Author(s): Yinghua Yang, Xiangrui Jiang, Lei Ao, Shengyi Dong, Xiumei Wu, Hualiang Jiang and Yu Zhao

Affiliation:

Keywords: Diaryl ether, 1-Phenylbutane-1,3-dione, Ullmann coupling reaction, Methyl 4-iodobenzoate, CuI, Coppercatalyzed

Abstract: 1-Phenylbutane-1,3-dione was found to be an efficient novel ligand for copper-catalyzed formation of diaryl ethers. With this ligand methyl 4-iodobenzoate reacted with various phenols to give the corresponding diaryl ethers with reasonable yields and efficiency. The optimized reaction was carried out at 100 °C using 1,4-dioxane as solvent, Cs2CO3 as base, CuI as the catalyst and 1-phenylbutane-1,3-dione as the ligand.

Cite this article as:

Yang Yinghua, Jiang Xiangrui, Ao Lei, Dong Shengyi, Wu Xiumei, Jiang Hualiang and Zhao Yu, An Efficient Novel Ligand for Copper-Catalyzed Formation of Diaryl Ethers, Letters in Organic Chemistry 2007; 4 (7) . https://dx.doi.org/10.2174/157017807782006281