Abstract
Aptamers have been introduced to analytical applications, target validation, and drug discovery processes and, recently, applied directly as therapeutic agents. Aptamers can be generated by a method called SELEX (Systematic Evolution of Ligands by Exponential Enrichment). This is quite remarkable for such a young technology, which is only created in the early 1990s. This paper reviews recent new applications of aptamers in stem cell research and tissue engineering.
Keywords: Mesenchymal stem cells, aptamer, FACS analysis
Mini-Reviews in Medicinal Chemistry
Title: Aptamer-Based Strategies for Stem Cell Research
Volume: 7 Issue: 7
Author(s): Ke-Tai Guo, Richard Schafer, Angela Paul, Gerhard Ziemer, Hans P. Wendel, Ke-Tai Guo, Richard Schafer, Angela Paul, Gerhard Ziemer and Hans P. Wendel
Affiliation:
Keywords: Mesenchymal stem cells, aptamer, FACS analysis
Abstract: Aptamers have been introduced to analytical applications, target validation, and drug discovery processes and, recently, applied directly as therapeutic agents. Aptamers can be generated by a method called SELEX (Systematic Evolution of Ligands by Exponential Enrichment). This is quite remarkable for such a young technology, which is only created in the early 1990s. This paper reviews recent new applications of aptamers in stem cell research and tissue engineering.
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Cite this article as:
Ke-Tai Guo , Richard Schafer , Angela Paul , Gerhard Ziemer , Hans P. Wendel , Guo Ke-Tai, Schafer Richard, Paul Angela, Ziemer Gerhard and Wendel P. Hans, Aptamer-Based Strategies for Stem Cell Research, Mini-Reviews in Medicinal Chemistry 2007; 7 (7) . https://dx.doi.org/10.2174/138955707781024481
DOI https://dx.doi.org/10.2174/138955707781024481 |
Print ISSN 1389-5575 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5607 |
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