Recent Progress in Measuring Structural Similarity Between Proteins

Title: Recent Progress in Measuring Structural Similarity Between Proteins

Volume: 8 Issue: 3

Author(s): Oliviero Carugo

Affiliation:

Keywords: Distance matrix ALIgnment (DALI), Delaunay Tessellation Comparisons, Combinatorial Extension algorithm, MolCom, SCOP database

Abstract: Surprisingly, after at least two decades of researches focused on the analysis of the similarity between protein three-dimensional structures, several new comparison methods were proposed during the last few years. These are briefly summarized and commented below. Some of the newly developed techniques are fast and were designed to handle large amounts of data and vast structural databases. Other methods are much slower and were developed to gain biological information by comparing distantly related protein structures. Additional studies were devoted to the problem of the multiple structural alignments and to strategies of comparison between alternative structural alignments..

Cite this article as:

Carugo Oliviero, Recent Progress in Measuring Structural Similarity Between Proteins, Current Protein & Peptide Science 2007; 8 (3) . https://dx.doi.org/10.2174/138920307780831839

DOI https://dx.doi.org/10.2174/138920307780831839	Print ISSN 1389-2037
Publisher Name Bentham Science Publisher	Online ISSN 1875-5550