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Protein & Peptide Letters

Editor-in-Chief

ISSN (Print): 0929-8665
ISSN (Online): 1875-5305

Molecular Simulations of Rhodopsin Tetrameter

Author(s): M. Witt, J. Ciarkowski and C. Czaplewski

Volume 14, Issue 4, 2007

Page: [381 - 387] Pages: 7

DOI: 10.2174/092986607780363916

Price: $65

Abstract

Di/oligomerization of G-protein coupled receptors (GPCRs) is well established, however very little is known regarding the interaction details. Current paper presents results of molecular dynamics simulations of theoretical model of rhodopsin tetramer with transducine (Gt) in lipid bilayer. Ligand-protein and receptor-receptor interactions have been proposed.

Keywords: Oligomerization, tetramer, GPCRs, rhodopsin, molecular dynamics


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