Recent Advances in the Development of Hybrid Molecules/Designed Multiple Compounds with Antiamnesic Properties

Title: Recent Advances in the Development of Hybrid Molecules/Designed Multiple Compounds with Antiamnesic Properties

Volume: 7 Issue: 3

Author(s): Michael Decker

Affiliation:

Keywords: Hybrid molecules, Multiple ligands, AChE inhibitors, Serotonin transporter (SERT), monoamine oxidase (MAO), lipoic acid, 5-HT3 receptor, Ca2+-channel blockers

Abstract: Novel compounds have been developed that (in many cases) inhibit cholinesterases and concomitantly interact with at least one further pharmacological target, such as 5-HT3 or H3 receptors. But also enzymes like monoamine oxidase and the serotonin transporter have been targeted. Hybrid molecules can also incorporate antioxidant or neuronal Ca2+- channel-blocking structures.

Cite this article as:

Decker Michael, Recent Advances in the Development of Hybrid Molecules/Designed Multiple Compounds with Antiamnesic Properties, Mini-Reviews in Medicinal Chemistry 2007; 7 (3) . https://dx.doi.org/10.2174/138955707780059817