Ionic Liquid/Silica Sulfuric Acid Promoted Fast Synthesis of a Biginelli-Like Scaffold Reaction

Ahmad      Shaabani; Afshin      Sarvary; Abbas      Rahmati; Ali Hossein      Rezayan

doi:10.2174/157017807780037531

Abstract

Biginelli-like scaffolds were synthesized in good yields by a three-component condensation reaction of 5,5-dimethyl-1,3-cyclohexanedione, an aldehyde and urea, N-methylurea or thiourea in 1-butyl-3- methylimidazolium bromide ([bmim]Br) as ionic liquid (IL) in the presence of silica sulfuric acid (SSA) as solid acid catalyst at 100 °C within less than 2 hours.

Keywords: Ionic liquid, silica sulfuric acid, Biginelli-like, [bmim]Br, catalyst, multi-component reaction

« Previous Next »

Rights & Permissions Print Cite

Letters in Organic Chemistry

Title: Ionic Liquid/Silica Sulfuric Acid Promoted Fast Synthesis of a Biginelli-Like Scaffold Reaction

Volume: 4 Issue: 1

Author(s): Ahmad Shaabani, Afshin Sarvary, Abbas Rahmati and Ali Hossein Rezayan

Affiliation:

Keywords: Ionic liquid, silica sulfuric acid, Biginelli-like, [bmim]Br, catalyst, multi-component reaction

Abstract: Biginelli-like scaffolds were synthesized in good yields by a three-component condensation reaction of 5,5-dimethyl-1,3-cyclohexanedione, an aldehyde and urea, N-methylurea or thiourea in 1-butyl-3- methylimidazolium bromide ([bmim]Br) as ionic liquid (IL) in the presence of silica sulfuric acid (SSA) as solid acid catalyst at 100 °C within less than 2 hours.

Export Options

Export File:

RIS (for EndNote, Reference Manager, ProCite)

BibTeX

Text

Content:

Citation Only

Citation and Abstract

About this article

Cite this article as:

Shaabani Ahmad, Sarvary Afshin, Rahmati Abbas and Rezayan Ali Hossein, Ionic Liquid/Silica Sulfuric Acid Promoted Fast Synthesis of a Biginelli-Like Scaffold Reaction, Letters in Organic Chemistry 2007; 4 (1) . https://dx.doi.org/10.2174/157017807780037531