Is There a Role for Cytokine Based Therapies in Fibromyalgia

Title: Is There a Role for Cytokine Based Therapies in Fibromyalgia

Volume: 12 Issue: 1

Author(s): Daniel J. Wallace

Affiliation:

Keywords: neuromuscular pain, hypothalamic-pituitary-adrenal (HPA) axis, non-inflammatory process, thyrotropin, lymphocyte proliferation responses, Chronic Fatigue Syndrome, rheumatology

Abstract: Cytokines are glycoproteins that serve as chemical messengers between cells. They assist in the regulation of cell growth and repair and also have immune modulating properties. Cytokines play a role in diverse clinical processes and phenomena such as fatigue, fever, sleep, pain, stress and aching. A review of the fibromyalgia literature and related studies suggest that IL-1, IL-6 and IL-8 are dysregulated in the syndrome. Therapies directed against these cytokines may be of potential importance in the management of fibromyalgia.

Cite this article as:

Wallace J. Daniel, Is There a Role for Cytokine Based Therapies in Fibromyalgia, Current Pharmaceutical Design 2006; 12 (1) . https://dx.doi.org/10.2174/138161206775193208