Abstract
Primary tracheal malignancies are very infrequent, and data relating to them is limited. We recently encountered an 82 yearold woman with a history of aortic stenosis, hypertension, and hypothyroidism, that presented to the clinic with cough and shortness of breath of six month duration. A computed tomography (CT) scan of the chest revealed tracheal thickening with nonspecific nodularity. The patient underwent fiberoptic bronchoscopy that revealed a tracheal mass with significant airway narrowing (Fig. 1). Biopsy of the tracheal mass revealed a tumor composed of small-to-medium size nests that contained lumen -forming eosinophil cells centrally, and smaller basaloid cells peripherally (Fig. 2). The cystic spaces within the basaloid cells made the diagnosis of adenoid cystic carcinoma. There was no evidence of tumor spread on positron emission tomography (PET) scan. Because of the extent of the lesion and in view of her pre-existing conditions, the patient elected non-operative treatment. Adenoid cystic carcinomas in the trachea are rare, but represent around 40% of all tracheal tumors.
Keywords: computed tomography (CT) scan, Primary tracheal malignancies, Biopsy, Adenoid cystic carcinomas
Current Respiratory Medicine Reviews
Title: Bronchoscopic Appearance of Tracheal Adenoid Cystic Carcinoma
Volume: 2 Issue: 4
Author(s): Salim Surani, Maqsood Ahmed, James Mullin and Joseph Varon
Affiliation:
Keywords: computed tomography (CT) scan, Primary tracheal malignancies, Biopsy, Adenoid cystic carcinomas
Abstract: Primary tracheal malignancies are very infrequent, and data relating to them is limited. We recently encountered an 82 yearold woman with a history of aortic stenosis, hypertension, and hypothyroidism, that presented to the clinic with cough and shortness of breath of six month duration. A computed tomography (CT) scan of the chest revealed tracheal thickening with nonspecific nodularity. The patient underwent fiberoptic bronchoscopy that revealed a tracheal mass with significant airway narrowing (Fig. 1). Biopsy of the tracheal mass revealed a tumor composed of small-to-medium size nests that contained lumen -forming eosinophil cells centrally, and smaller basaloid cells peripherally (Fig. 2). The cystic spaces within the basaloid cells made the diagnosis of adenoid cystic carcinoma. There was no evidence of tumor spread on positron emission tomography (PET) scan. Because of the extent of the lesion and in view of her pre-existing conditions, the patient elected non-operative treatment. Adenoid cystic carcinomas in the trachea are rare, but represent around 40% of all tracheal tumors.
Export Options
About this article
Cite this article as:
Surani Salim, Ahmed Maqsood, Mullin James and Varon Joseph, Bronchoscopic Appearance of Tracheal Adenoid Cystic Carcinoma, Current Respiratory Medicine Reviews 2006; 2 (4) . https://dx.doi.org/10.2174/157339806778777203
DOI https://dx.doi.org/10.2174/157339806778777203 |
Print ISSN 1573-398X |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6387 |
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
Related Articles
-
Myocardial Infarction in Systemic Lupus Erythematosus – the Sex-Specific Risk Profile
Current Pharmaceutical Design Garlic-Derived Allyl Sulfides in Cancer Therapy
Anti-Cancer Agents in Medicinal Chemistry Use of Peripheral Blood Stem Cells in Tissue Engineering
Current Tissue Engineering (Discontinued) Design, Synthesis, and Bioactivity of Pyrazole Acid Derivatives as Endothelin Receptor Antagonists
Medicinal Chemistry Metastasis-Inducing S100A4 Protein: Implication in Non-Malignant Human Pathologies
Current Molecular Medicine Exploiting High-Throughput Ion Channel Screening Technologies in Integrated Drug Discovery
Current Pharmaceutical Design Hemodynamic Regulation of Metallopeptidases within the Vasculature
Protein & Peptide Letters Atypical Chest Pain in ACS: A Trap Especially for Women
Current Pharmaceutical Design Gender Differences in Autonomic Control of the Cardiovascular System
Current Pharmaceutical Design Antihypertensive Efficacy and Tolerability of Aliskiren/Amlodipine Single- Pill Combinations in Patients with an Inadequate Response to Aliskiren Monotherapy¥
Current Vascular Pharmacology Optical Imaging of Microvascular Morphology and Perfusion
Current Angiogenesis (Discontinued) Calcium Metabolism and Oxidative Stress in Bone Fractures: Role of Antioxidants
Current Drug Metabolism Regulation of the Sodium-Phosphate Cotransporter Pit-1 and its Role in Vascular Calcification
Current Vascular Pharmacology Associations between Alzheimer’s Disease and Blood Homocysteine, Vitamin B<sub>12</sub>, and Folate: A Case-Control Study
Current Alzheimer Research The Role of Melatonin in Rheumatic Diseases
Infectious Disorders - Drug Targets Diet Bioactive Compounds: Implications for Oxidative Stress and Inflammation in the Vascular System
Endocrine, Metabolic & Immune Disorders - Drug Targets Preface
Current Cancer Drug Targets PKC Delta and Epsilon in Drug Targeting and Therapeutics
Recent Patents on DNA & Gene Sequences Cell-Penetrating Peptides as a Potential Drug Delivery System for Effective Treatment of Diabetes
Current Pharmaceutical Design Plasma Ghrelin Levels in Patients with Familial Mediterranean Fever
Protein & Peptide Letters