Anti-tumor Therapeutic Molecules that Target the Programmed Cell Death Machinery

Title: Anti-tumor Therapeutic Molecules that Target the Programmed Cell Death Machinery

Volume: 6 Issue: 9

Author(s): Iva Ivanovska, Clare N. Muhoro and Pablo M. Irusta

Affiliation:

Keywords: Cancer, apoptosis, IAP, Caspases, Bcl-2

Abstract: Apoptosis is a process that governs the elimination of unwanted, damaged, or infected cells in most organisms. Defects in its execution are associated with several diseases, including cancer. Herein, we discuss novel molecules with potential anti-tumor activity that target components of the apoptotic machinery, specifically Bcl-2 proteins, IAPs and caspases.

Cite this article as:

Ivanovska Iva, Muhoro N. Clare and Irusta M. Pablo, Anti-tumor Therapeutic Molecules that Target the Programmed Cell Death Machinery, Mini-Reviews in Medicinal Chemistry 2006; 6 (9) . https://dx.doi.org/10.2174/138955706778195216