Efficient Solvent-Free Synthesis of Quinolines Promoted by BiCl3

Title: Efficient Solvent-Free Synthesis of Quinolines Promoted by BiCl3

Volume: 3 Issue: 4

Author(s): Guan-Wu Wang and Cheng-Sheng Jia

Affiliation:

Keywords: solvent-free., BiCl3, Friedländer reaction, α-methylene ketones, o-aminoaryl ketones, Quinoline

Abstract: Poly-substituted quinolines are readily prepared in excellent yields via a Friedlander reaction of oaminoarylketone or o-aminoarylaldehyde with α-methylene ketones in the presence of BiCl3 under solventfree and thermal heating conditions.

Cite this article as:

Wang Guan-Wu and Jia Cheng-Sheng, Efficient Solvent-Free Synthesis of Quinolines Promoted by BiCl3, Letters in Organic Chemistry 2006; 3 (4) . https://dx.doi.org/10.2174/157017806776114568