Abstract
The molecular diversity of bovine τ obtained by three different preparation protocols was characterized by immunoblot analyses after two-dimensional gel electrophoresis. These analyses revealed that t was heterogeneously modified, that is, up to 20 spots separated along the pH gradient, mostly independent of the preparation protocol.
Keywords: Alzheimer's disease, mass spectrometry, PHF-τ, phosphoprotein stain, phosphorylation, septin
Protein & Peptide Letters
Title: Characterization of Bovine Tau-Preparations by Two-Dimensional Gel Electrophoresis
Volume: 13 Issue: 6
Author(s): Daniela Volke and Ralf Hoffmann
Affiliation:
Keywords: Alzheimer's disease, mass spectrometry, PHF-τ, phosphoprotein stain, phosphorylation, septin
Abstract: The molecular diversity of bovine τ obtained by three different preparation protocols was characterized by immunoblot analyses after two-dimensional gel electrophoresis. These analyses revealed that t was heterogeneously modified, that is, up to 20 spots separated along the pH gradient, mostly independent of the preparation protocol.
Export Options
About this article
Cite this article as:
Volke Daniela and Hoffmann Ralf, Characterization of Bovine Tau-Preparations by Two-Dimensional Gel Electrophoresis, Protein & Peptide Letters 2006; 13 (6) . https://dx.doi.org/10.2174/092986606777145805
DOI https://dx.doi.org/10.2174/092986606777145805 |
Print ISSN 0929-8665 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5305 |
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
Related Articles
-
Treatment of Leishmaniasis: A Review and Assessment of Recent Research
Current Pharmaceutical Design Methodologies for Investigating Natural Medicines for the Treatment of Nonalcoholic Fatty Liver Disease (NAFLD)
Current Pharmaceutical Biotechnology Glycans and Glycan-Binding Proteins in Brain: Galectin-1-Induced Expression of Neurotrophic Factors in Astrocytes
Current Drug Targets The Animal Models of Dementia and Alzheimer’s Disease for Pre-Clinical Testing and Clinical Translation
Current Alzheimer Research Therapeutic DNA Delivery to Skeletal Muscle
Current Genomics Potential Therapeutic Targets in Cirrhotic Cardiomyopathy
Cardiovascular & Hematological Disorders-Drug Targets Synaptic Activity-Regulated Wnt Signaling in Synaptic Plasticity, Glial Function and Chronic Pain
CNS & Neurological Disorders - Drug Targets Amyloid Forming Proteases: Therapeutic Targets for Alzheimers Disease
Current Pharmaceutical Design The α2δ Subunit and Absence Epilepsy: Beyond Calcium Channels?
Current Neuropharmacology Pathophysiological Role of Hepatocyte Nuclear Factor 6 in Negative Regulation of Hepatic Apoptosis: A Novel Hypothesis
Current Molecular Medicine Wnt Signaling in Development, Disease and Translational Medicine
Current Drug Targets A Systematic Review and Meta-analysis of Clinical Studies on Ankylosing Spondylitis and Neutrophil to Lymphocyte Ratio
Current Rheumatology Reviews Encountering and Advancing Through Antiangiogenesis Therapy for Gliomas
Current Pharmaceutical Design Edema, Inflammation and Fibrosis – Comparison Between Catecholamine- and Hypoxia-Induced Pulmonary Injuries
Vascular Disease Prevention (Discontinued) VEGF/VEGFR Pathway Inhibitors as Anti-Angiogenic Agents: Present and Future
Current Cancer Drug Targets Immune-Neuroendocrine Interactions Involving Thymus and Pineal Gland in Stem Cell Therapy of Age-Related Diseases
Immunology, Endocrine & Metabolic Agents in Medicinal Chemistry (Discontinued) Novel Possible Pharmaceutical Research Tools: Stem Cells, Gene Delivery and their Combination
Current Pharmaceutical Design Intravascular Targeting of a New Anticoagulant Heparin Compound
Cardiovascular & Hematological Disorders-Drug Targets Ewing’s Sarcoma Cancer Stem Cell Targeted Therapy
Current Stem Cell Research & Therapy Targeted Therapy Options for Treatment of Bone Metastases; Beyond Bisphosphonates
Current Pharmaceutical Design