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Protein & Peptide Letters

Editor-in-Chief

ISSN (Print): 0929-8665
ISSN (Online): 1875-5305

Synthesis of Peptidyl Ureas Employing O-succinimidyl-(9H-fluoren-9- ylmethoxycarbonylamino)methylcarbamate Derivatives as Activated Monomers

Author(s): Vommina V. Sureshbabu, Naremaddepalli S. Sudarshan and Gundala C. Krishna

Volume 13, Issue 5, 2006

Page: [493 - 498] Pages: 6

DOI: 10.2174/092986606776819556

Price: $65

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Abstract

A convenient and efficient method for the synthesis of dipeptidyl ureas and urea acids employing Osuccinimidyl-( 9H-fluoren-9-ylmethoxycarbonyl amino)methylcarbamates has been described. All the compounds, obtained in good yields, have been fully characterized by mass and NMR spectra.

Keywords: dichloromethane (DCM), Dipeptidyl Urea Acids, NMR, protease, Schotten-Baumann conditions


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