Isosteviol as a Starting Material in Organic Synthesis

Title: Isosteviol as a Starting Material in Organic Synthesis

Volume: 15 Issue: 15

Author(s): Nico Moons, Wim De Borggraeve and Wim Dehaen

Affiliation:

Keywords: Derivatisation, diterpene, hydroxylation, isosteviol, rearrangements, stevioside, supramolecular, ringtransformation, aglycones, diterpene derivatives, steviol, stevia glycosides, stereoselectivities

Abstract: In recent years the diterpene isosteviol, obtained via acid catalyzed rearrangement of stevioside, has gained growing interest by scientists. Its structural features and easy accessibility make isosteviol a useful starting material in organic synthesis. In this review, we group all existing modifications to the isosteviol moiety, ranging from biological transformation to rearrangements of the terpene skeleton. We will also discuss the known macrocycles based on isosteviol

Cite this article as:

Moons Nico, De Borggraeve Wim and Dehaen Wim, Isosteviol as a Starting Material in Organic Synthesis, Current Organic Chemistry 2011; 15 (15) . https://dx.doi.org/10.2174/138527211796367372