Towards the Targeted Therapy of Melanoma

K.   S.M.   Smalley; M.      Herlyn

doi:10.2174/138955706776361402

Abstract

Novel anti-cancer treatments use knowledge about the underlying biology of the tumor to find suitable molecular targets. The recent years have seen great advances in understanding the biology of melanoma. In the current review we discuss the most promising molecular targets for melanoma and suggest possible strategies for overcoming resistance.

Keywords: Melanoma, melanocyte, BRAF, PI3K, therapy, cancer, proteasome

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