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Letters in Drug Design & Discovery

Editor-in-Chief

ISSN (Print): 1570-1808
ISSN (Online): 1875-628X

Synthesis and Evaluation of Hypolipidemic Properties of some Novel Derivatives of Thieno Oxazine and 5-Hydroxyindole-2-Carboxylic Acid

Author(s): Sankar Mohan, K. A. Reddy, Javed Iqbal, Debnath Bhuniya and Saibal K. Das

Volume 3, Issue 3, 2006

Page: [179 - 182] Pages: 4

DOI: 10.2174/157018006776287014

Price: $65

Abstract

Two series of molecules were synthesized with carboxamidomethyl linker utilizing thieno oxazine and 5-Hydroxyindole-2-carboxylic acid. In vivo studies of these molecules indicated that molecules from each series, 4h and 5b, are very potent triglyceride lowering agents.

Keywords: Synthesis, thieno oxazine, indole carboxylic acid, hypolipidemic properties, triglyceride


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