Insights into Amyloid Fibril Formation from Mass Spectrometry

Title: Insights into Amyloid Fibril Formation from Mass Spectrometry

Volume: 13 Issue: 3

Author(s): Gemma L. Caddy and Carol V. Robinson

Affiliation:

Keywords: Mass spectrometry, amyloidogenic, hydrogen exchange, protein conformation

Abstract: Mass spectrometry has become increasingly important in amyloid research specifically in the mechanism of formation and characterization of fibrils. In this review we highlight key experiments that provide evidence for different conformations, interactions and unfolding intermediates in proteins associated with amyloid diseases.

Cite this article as:

Caddy L. Gemma and Robinson V. Carol, Insights into Amyloid Fibril Formation from Mass Spectrometry, Protein & Peptide Letters 2006; 13 (3) . https://dx.doi.org/10.2174/092986606775338416

DOI https://dx.doi.org/10.2174/092986606775338416	Print ISSN 0929-8665
Publisher Name Bentham Science Publisher	Online ISSN 1875-5305