Abstract
Recent progress in the synthesis and use of enaminonitriles as precursors for carbocyclic and heterocyclic compounds is reviewed. The synthetic routes for preparation of enaminonitriles are based on addition and condensation reactions. Enaminonitriles can be used as building blocks for carbocyclic, five, six, and seven-membered heterocycles as well as fused heterocyclic compounds. Biological and industrial applications of heterocycles derived from enaminonitriles are also discussed.
Keywords: Enaminonitriles, Synthesis, Dimethylformamide-dimethylacetal, N-nucleophiles, C-nucleophiles, Heterocycles
Call for Papers in Thematic Issues
Catalytic C-H bond activation as a tool for functionalization of heterocycles
The major topic is the functionalization of heterocycles through catalyzed C-H bond activation. The strategies based on C-H activation not only provide straightforward formation of C-C or C-X bonds but, more importantly, allow for the avoidance of pre-functionalization of one or two of the cross-coupling partners. The beneficial impact of ...read more
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