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Current Drug Targets

Editor-in-Chief

ISSN (Print): 1389-4501
ISSN (Online): 1873-5592

EGFR(S) Inhibitors in the Treatment of Gastro-Intestinal Cancers: Whats New?

Author(s): Shailender Singh Kanwar, Jyoti Nautiyal and Adhip P.N. Majumdar

Volume 11, Issue 6, 2010

Page: [682 - 698] Pages: 17

DOI: 10.2174/138945010791170851

Price: $65

Abstract

In the past 10 to 15 years, a considerable progress has been made in the treatment of gastrointestinal (GI) related malignancies, as a number of agents expanded from only one in 1995 to seven in 2006. Current review describes the recent role of targeted therapies, specifically EGFR inhibitors in the treatment of GI cancers. Importance of dietary agents in the treatment and prevention of GI cancers is also reviewed.

Keywords: EGFR inhibitors, colon cancer, apoptosis


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