Abstract
Modern organic synthesis requires easily obtainable synthetic building blocks that can be manipulated without the need of severe reaction conditions and that show high chemical versatility so that they can be employed in diverse synthetic processes. β- Nitroacrylates are a class of electron-poor alkenes having two electron-withdrawing groups in α- and β-positions. This peculiarity makes their chemical behaviour more interesting with respect to the classical conjugated nitroalkenes and, in the last few years, there has been a growing interest in the chemistry of these molecules. The aim of this report is to present, mainly, the recent synthetic applications of β- nitroacrylates, as well as the principal procedures for their preparations.
Call for Papers in Thematic Issues
Catalytic C-H bond activation as a tool for functionalization of heterocycles
The major topic is the functionalization of heterocycles through catalyzed C-H bond activation. The strategies based on C-H activation not only provide straightforward formation of C-C or C-X bonds but, more importantly, allow for the avoidance of pre-functionalization of one or two of the cross-coupling partners. The beneficial impact of ...read more
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